Biventricular cardiac metastasis from vulvar squamous cell carcinoma

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Published May 30, 2022
DOI: https://doi.org/10.22551/2022.35.0902.10205
Stefan Spinu http://orcid.org/0000-0002-9526-5620 Daniel Sur http://orcid.org/0000-0002-0926-4614 Andreea Parv http://orcid.org/0000-0002-9509-3988 Calin Cainap Petruta Stoia Veronica Creciun Madalina Bota Alina Pop Ovidiu Bochis

Abstract

Vulvar cancers make up just 3% to 5% of all gynecological cancers, and they are most typically found in postmenopausal women. Vulvar cancer distant metastases are uncommon and usually arise late. Only six cases of vulvar cancer metastasizing to the heart have been reported in the literature, and none of them included both the left and right ventricles. We describe the case of a 68-year-old patient diagnosed with vulvar cancer arising from lichen sclerosus, initially localized, treated with chemotherapy, surgery, and radiation therapy. Less than two months after the end of the treatment sequence, the patient returned to our clinic with bone pain. Imaging investigations have shown multiple disseminated metastases, but not in the heart at that moment. Chemotherapy was initiated, and after two cycles, the patient developed an arrhythmia (atrial fibrillation with rapid ventricular rate), which was later determined to be caused by cardiac metastases discovered by echocardiography and computed tomography. Vulvar cancer metastatic to the heart represents a rare clinical condition, requiring multidisciplinary care. The case's uniqueness is the biventricular metastasis, which resulted in STEMI despite angiographically normal epicardial coronary arteries.

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Keywords

vulvar squamous cell carcinoma, cardiac metastasis, natural history, heart arrhythmia

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How to Cite
Spinu, S., Sur, D., Parv, A., Cainap, C., Stoia, P., Creciun, V., Bota, M., Pop, A., & Bochis, O. (2022). Biventricular cardiac metastasis from vulvar squamous cell carcinoma. Archive of Clinical Cases, 9(2), Arch Clin Cases 2022; 9(2):62-68. https://doi.org/10.22551/2022.35.0902.10205
Issue
Vol. 9 No. 2 (2022)
Section
Case Reports

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How to Cite

Spinu, S., Sur, D., Parv, A., Cainap, C., Stoia, P., Creciun, V., Bota, M., Pop, A., & Bochis, O. (2022). Biventricular cardiac metastasis from vulvar squamous cell carcinoma. Archive of Clinical Cases, 9(2), Arch Clin Cases 2022; 9(2):62-68. https://doi.org/10.22551/2022.35.0902.10205