Feltys syndrome – a rare case of febrile neutropenia

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Published Jul 20, 2019
DOI: https://doi.org/10.22551/2019.23.0602.10153
Luís Rodrigues Glória Nunes da Silva António Pais de Lacerda

Abstract

Feltys syndrome (rheumatoid arthritis with neutropenia and splenomegaly) is a rare condition with poor long-term prognosis, mainly as a result of severe infection risk. An effective treatment strategy has not been developed so far and current treatment options are based upon case reports, small series and clinical experience since no randomized clinical trials are available. The authors describe the case of a 53-year-old female patient with a 14-year history of rheumatoid arthritis presenting with fever, neutropenia and splenomegaly. Broad-spectrum antibiotics and granulocyte colony-stimulating factor were administered with good clinical outcome and low dose methotrexate for disease control was successfully initiated after discharge. We would like to highlight the importance of being aware of this syndrome in the differential diagnosis of long term rheumatoid arthritis patients presenting with febrile neutropenia.

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Keywords

Feltys syndrome, rheumatoid arthritis, febrile neutropenia

References
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How to Cite
Rodrigues, L., da Silva, G. N., & de Lacerda, A. P. (2019). Feltys syndrome – a rare case of febrile neutropenia. Archive of Clinical Cases, 6(2), Arch Clin Cases 2019; 6(2):48-52. https://doi.org/10.22551/2019.23.0602.10153
Issue
Vol. 6 No. 2 (2019)
Section
Case Reports

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How to Cite

Rodrigues, L., da Silva, G. N., & de Lacerda, A. P. (2019). Feltys syndrome – a rare case of febrile neutropenia. Archive of Clinical Cases, 6(2), Arch Clin Cases 2019; 6(2):48-52. https://doi.org/10.22551/2019.23.0602.10153