Pyoderma gangrenosum: a rare disease with a rare localization

Ionela-Alina Grosu, Delia Gabriela Ciobanu-Apostol, Dan Vâță, Elena Andrese, Laura Gheucă-Solovăstru, Laura Stătescu

Abstract


Pyoderma gangrenosum (PG) is a rare neutrophilic inflammatory disease, characterized by necrotizing and painful ulcers of unknown cause, that it is often misinterpreted. PG is usually idiopathic and includes dysregulation of the autoimmune system and frequently has an association with other systemic diseases (inflammatory bowel disease, rheumatological, hematological disease or malignancy). The most common localization is on the lower legs, mainly in the pretibial area. We describe a case of Pyoderma gangrenosum in a 43 year-old female patient with erythemato-edematous big plaque, covered with sphacelous, yellow-green pus, localized on the left inguinal area and pubic area, which is a rare localization of this disease.


Keywords


pyoderma gangrenosum, idiopathic disease, ulceration, pubic area

Full Text:

PDF

References


Conrad C, Trüeb RM. Pyoderma gangrenosum. J Dtsch Dermatol Ges 2005; 3(5):334–342.

Brocq L. Nouvelle contribution a l'étude du phagédénisme géométrique. Ann Dermatol Syphiligr 1916; 6:1–39.

Brunsting AL, Goeckerman WH, O'Leary PA. Pyoderma gangrenosum: clinical and experimental observation in five cases occuring in adults. Arch Derm Syphilol 1930; 22: 655–80.

Braswell SF, Kostopoulos TC, Ortega-Loayza AG. Pathophysiology of pyoderma gangrenosum (PG): an updated review. J Am Acad Dermatol 2015; 73(4):691-8. [Article in Press]

Pereira N, Brites MM, Gonçalo M, Tellechea O, Figueiredo A. Pyoderma gangrenosum--a review of 24 cases observed over 10 years. Int J Dermatol 2013; 52(8):938-45.

Ahronowitz I, Harp J, Shinkai K. Etiology and management of pyoderma gangrenosum: a comprehensive review. Am J Clin Dermatol 2012; 13(3):191-211.

Cabalag MS, Wasiak J, Lim SW, Raiola FB. Inpatient management of pyoderma gangrenosum: treatments, outcomes, and clinical implications. Ann Plast Surg 2015; 74(3):354-60.

Al Ghazal P, Herberger K, Schaller J, et al. Associated factors and comorbidities in patients with pyoderma gangrenosum in Germany: a retrospective multicentric analysis in 259 patients. Orphanet J Rare Dis 2013; 8:136.

Su WP, Davis MD, Weenig RH, Powell FC, Perry HO. Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria. Int J Dermatol 2004; 43(11):790-800.

Adışen E, Erduran F, Gürer MA. Pyoderma Gangrenosum: A Report of 27 Patients. Int J Low Extrem Wounds 2016; 15(2):148-54.

Al Ghazal P, Dissemond J. Therapy of pyoderma gangrenosum in Germany: results of a survey among wound experts. J Dtsch Dermatol Ges 2015; 13(4):317-24.

Binus AM, Qureshi AA, Li VW, Winterfield LS. Pyoderma gangrenosum: a retrospective review of patient characteristics, comorbidities and therapy in 103 patients. Br J Dermatol 2011; 165(6):1244-50.

Callen JP, Jackson JM. Pyoderma gangrenosum: an update. Rheum Dis Clin North Am 2007; 33(4):787-802, vi.

Dabade TS, Davis MD. Diagnosis and treatment of the neutrophilic dermatoses (pyoderma gangrenosum, Sweet's syndrome). Dermatol Ther 2011; 24(2):273-84.

Gameiro A, Pereira N, Cardoso JC, Gonçalo M. Pyoderma gangrenosum: challenges and solutions. Clin Cosmet Investig Dermatol 2015; 8:285-93.




DOI: http://dx.doi.org/10.22551/2016.13.0304.10083

Copyright (c) 2016 Ionela-Alina Grosu, Delia Gabriela Ciobanu-Apostol, Dan Vâță, Elena Andrese, Laura Gheucă-Solovăstru, Laura Stătescu

Creative Commons License
Archive of Clinical Cases is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

 

ISSN: 2360-6975