Metastatic colorectal adenocarcinoma of mandible
Abstract
Oral metastasis from the colon is quite rare with limited reporting and scientific evidence. The most common metastasis from colorectal cancer is to the liver followed by lungs, bones, and other organs. However rare occurrences like metastasis to the oral cavity might worsen the prognosis and treatment outcome. Oral metastatic tumors account only 1% of all the malignant neoplasms of the jaw. In most of the cases metastasis has been reported in the jaw bones compared to soft tissues. Persistent pain and delayed, prolonged healing should raise the question of an underlying lesion. An unusual case of secondary oral metastasis presenting as an ulcero-proliferative growth in left mandibular alveolus from the primary colon adeno carcinoma has been reported.
##plugins.themes.bootstrap3.article.details##
colorectal adenocarcinoma, oral metastasis, mandibular alveolus, orthopantomography
2. Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ. Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer. Int J Mol Sci. 2017 Jan 19;18(1):197. doi: 10.3390/ijms18010197. PMID: 28106826; PMCID: PMC5297828.
3. Singh T, Amirtham U, Satheesh CT, et al. Floor-of-mouth metastasis in colorectal cancer. Ann Saudi Med. 2011 Jan-Feb;31(1):87-9. doi: 10.4103/0256-4947.70583. PMID: 20864784; PMCID: PMC3101733.
4. Moffat DA. Metastatic adenocarcinoma of the rectum presenting as an epulis: a case report. Br J Oral Surgery. 1976;14:90–2. https://doi.org/10.1016/0007-117X(76)90100-1.
5. Alvarez-Alvarez C, Iglesias-Rodríguez B, Pazo-Irazu S, Delgado-Sánchez-Gracián C. Colonic adenocarcinoma with metastasis to the gingiva. Med Oral Patol Oral Cir Bucal. 2006 Jan 1;11(1):E85-7. English, Spanish. PMID: 16388302.
6. Tomikawa M, Higuchi Y, Saku M, et al. Carcinoma of the colon metastatic to the lower gingiva. Dig Surg. 2001;18(4):333-5. doi: 10.1159/000050166. PMID: 11528150.
7. Kawamusa M. Gingival metastases from rectal cancer. J Gastrointest Surg. 2007;11:1.
8. Yoshito A. An autopsy case of rectal carcinoma with metastases to the oral region. Higushi Nippon J. 1997;16:295–9.
9. Rentschler RE, Thrasher TV. Gingival and mandibular metastases from rectal adenocarcinoma: case report and 20 year review of the English literature. Laryngoscope. 1982 Jul;92(7 Pt 1):795-7. doi: 10.1288/00005537-198207000-00015. PMID: 7045554.
10. Rusthoven JJ, Fine S, Thomas G. Adenocarcinoma of the rectum metastatic to the oral cavity. Two cases and a review of the literature. Cancer. 1984 Sep 15;54(6):1110-2. doi: 10.1002/1097-0142(19840915)54:6<1110::aid-cncr2820540631>3.0.co;2-o. PMID: 6088018.
11. Salvador JC, Rosa D, Rito M, Borges A. Atypical mandibular metastasis as the first presentation of a colorectal cancer. BMJ Case Rep. 2018 Jun 4;2018:bcr2018225094. doi: 10.1136/bcr-2018-225094. PMID: 29866691; PMCID: PMC5990096.
12. Kumar G, Manjunatha B. Metastatic tumors to the jaws and oral cavity. J Oral Maxillofac Pathol. 2013 Jan;17(1):71-5. doi: 10.4103/0973-029X.110737. PMID: 23798834; PMCID: PMC3687193.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Archive of Clinical Cases is protected by copyright and may be used in accordance with copyright and other applicable laws. Content available at www.clinicalcases.eu and our digital applications is intended for personal noncommercial use.
Authors who submit a manuscript for publication in Archive of Clinical Cases agree to the following terms: a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) only after the final version of the manuscript was accepted and published, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). d. It is compulsory that before submission authors ensure that their work was not published in any other medical journals or pending acceptance for publication and that "Archives of Clinical Cases" is the only beneficiary at that moment if their work/case will be accepted by us.
Guidelines for linking to www.clinicalcases.eu a. The main purpose of the site linking to the Archive of Clinical Casess site should be educational. b. Links should be made to the Archive of Clinical Casess home page (www.clinicalcases.eu) or to the articles abstract. c. It is forbidden to use the Archive of Clinical Casess cover by outside organizations unless permission has been granted in advance, notifying our Secretary. d. Material owned by the Archive of Clinical Cases (including the name, logo, cover, and text) may not be used in any manner that may induce the idea or suggest that the Archive of Clinical Cases is in some way recommending a specific company, product or service. e. You must not use or allow others to access or use, all or any part of our Site or the contents and/or applications on it for commercial purposes without our permission. To seek permission to do anything prohibited by or not contained in these TERMS, or which requires our prior consent or agreement, you can contact us.